Florida Hospital Cancer Institute ›› Cancer Programs ›› Paul A. Mancuso, MD, FACS, FASCRS

Paul A. Mancuso, MD, FACS, FASCRS is board certified in colon and rectal surgery and general surgery. He specializes in robotic and minimally invasive surgical interventions for colorectal and anal cancer as well as benign conditions involving the lower gastrointestinal tract. With more than a decade of clinical experience, he joins the Center for Colon & Rectal Surgery from Dr. Phillips Hospital in Orlando, where he was director of minimally invasive surgery and chairman of the robotics steering committee. He is a Clinical Assistant Professor of Surgery at Florida State University’s College of Medicine (Orlando campus) and Assistant Professor of Medicine at University of Central Florida.  With regular involvement in multidisciplinary conferences and medical cases, and surgical innovatios to address pelvic floor, pathology and GI tumors, Dr. Mancuso offers a true collaborative approach to solving problems of the colon and rectum - from the common to the complex.


  • Clinical Instructor, Colorectal Fellowship Program, Center for Colon & Rectal Surgery
  • Assistant Professor, University of Central Florida College of Medicine
  • Board Certified, Colon and Rectal Surgery
  • Board Certified, General Surgery
  • Fellow, American Society of Colon and Rectal Surgeons and American College of Surgeons
  • Fellowship, Colon and Rectal, Thomas Jefferson University, Philadelphia, PA
  • Residency, General Surgery, University Hospital - SUNY at Stony Brook, NY
  • Medical Degree, St. George's University, Grenada, WI
  • Master of Science, St. George's University, Grenada, WI
  • Member, American Medical Association, Florida Medical Association, Florida Society of Colon and Rectal Sureons, Piedmont Scoeity of Colon and Rectal Surgeons and Scoiety of American Gastrointestinal and Endoscopic Surgeons


  • Anal fistulas
  • Anal fissures
  • Anal, rectal and colon cancer
  • Anoscopy, Colonoscopy, Proctosigmoidoscopy and Sigmoidoscopy
  • Colorectal Cancer Surgery
  • Crohn’s Disease
  • Diverticulitis
  • Fecal Inconctinence
  • General Colon & Rectal Surgery
  • Hemorrhoids
  • Minimally Invasive Laparoscopic Surgery
  • Rectal Prolapse
  • Rectal and vaginal fistulas
  • Robotic Surgery
  • Ulcerative colitis